Endocrine Abstracts

Aim: Non-alcoholic steatohepatitis is one of the most common causes of chronic liver disease and the incidence in the population varies from %10–24. TGF- β –1 is the most important TGF- β isoform responsible for fibrosis and its effect on hepatic fibrosis was demonstrated in-vitro and in chronic viral hepatitis. Besides TGF- β is an immunsuppresive cytokine and it is known that low TGF- β activity can trigger autoimmune diseases and inflammation.<...

Introduction: Whether subclinical hypothyroidism (SCH) is related to risk for cardiovascular disease is controversial. Inflammation and oxidation of lipoproteins play an important role in the progression and complications of atherosclerosis.Therefore we aimed to evaluate the plasma levels of thiobarbituric acid reactive substances (TBARS) as a marker of oxidative stress, high sensitive CRP (hsCRP) and lipid profile as a risk factor for atherosclerosis in...

Introduction: Although the etiology of osteoporosis is different between men and women, the underlying pathophysiologic mechanism is similar, namely an absolute or relative increase in bone resorption, leading to progressive bone loss. Transforming growth factor (TGF) beta-1 is a growth factor in human bone, which is produced by osteoblasts and inhibits osteoclast proliferation and activity and stimulates proliferation and differentiation of preosteoblasts.<p class="abstex...